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Jiahn Oh, 3r hr Biology Enhanced

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BC: Work Cited URL | Pictures http://www.pyroenergen.com/articles07/downs-syndrome.htm http://www.netterimages.com/image/10672.htm http://learn.genetics.utah.edu/content/disorders/whataregd/down/ http://en.wikipedia.org/wiki/John_Langdon_Down http://www.healthwatchcenter.com/2010/08/down-syndrome-treatment-and-therapies/ | Information http://health.naver.com/medical/disease/detail.nhn?selectedTab=detail&diseaseSymptomTypeCode=AA&diseaseSymptomCode=AA000074&cpId=CP00038907 http://en.wikipedia.org/wiki/John_Langdon_Down http://learn.genetics.utah.edu/content/disorders/whataregd/down/ http://en.wikipedia.org/wiki/Down_syndrome http://thebrooklynink.com/2011/11/14/35913-for-down-syndrome-adults-an-uncertain-future/

FC: Down Syndrome | Jiahn Oh 3rd hr Biology Enhanced

1: Down Syndrome | Down Syndrome is developmental disorder that is caused by the extra copy of chromosome 21. So instead of having two for a pair, it has three chromosome 21. This is the most common chromosomal disorder, and it causes a lot of symptoms such as mental retardation, slowness of growth and abnormality of certain parts of the body. You can usually tell weather the person has Down syndrome or not by the appearance because they have similar characteristics; small head, flat nose, eyes that slanted upwards and short neck.

2: History | Down Syndrome had first described by a British physician called John L.Down in 1886. He was curious about the children who were born with similar biological characteristics. Although he could not find the cause of it ,he named it "Mongolism", because these kids were unfamiliar to him, he thought they were Asians. After he died, in 1958, a French geneticist, Jérme Lejeune discovered the cause of it and published it by the name Down Syndrome. | John Langdon Down

3: Cause | This picture is a gene map of a person who has Down Syndrome. As you can see, chromosome 21 has three copies instead of two. When nondisjusction occurs in the egg cell, which means a pair of chromosomes fail to separate during egg(or sperm) formation. So after this, when sperm and egg fuse, they end up having 3 chromosome 21. Babies of the women who are old are more likely to have Down Syndrome.

4: Symptoms | People who have Down Syndrome has similar characteristics of their appearance. They have a flat face, a small round nose, abnormally shaped ears, a large tongue, separation of big toe and second toe, and upward slanting eyes with small folds of skin in the corners.Not just these, | they have low intelligence and slow growth rate. Also they have increased risk of having other medically significant problems like leukemia, hearing loss and hypothyroidism. Because of all these, they mostly have short like expectancy.

5: Treatments | There is no cure for Down Syndrome, but having curtain treatments such as physical therapy or speech therapy for it is very important to help slow down the developments of abnormality. Also, people who has Down Syndrome are vulnerable to get other disorders like hearing disorder, heart disease, and disorder of the dijest organs, so they should checkup regularly.

6: Future (Adulthood) | In the past, Down Syndrome has considered as threatening genetic disorder because people who were suffering from it died very early, often from complications like heart defect, . For example, in 1983, average life expectancy for American who has Down Syndrome was 25 years. But now, because of the increase of awareness and medical and health care service, the average life expectancy of the Down syndrome population has risen to about 50 to 60 years. Nowadays, Down Syndrome is popular among people(1 in every 691), so many people don't see them with narrow mind. Although people who has Down Syndrome usually can't have professional jobs can do part-time jobs, and also the government supports them . There are many social residential facilities especially for people who has Down Syndrome if their parents die or not able to take care of them.

7: Current News | "For High School Athlete With Down Syndrome, Age Is an Issue" -April 12, 2012 by Tim Rohan http://query.nytimes.com/gst/fullpage.html?res=9E05E2DF1F31F931A25757C0A9649D8B63 | Summary: Eric Dompierre, who have Down Syndrome, and plays basketball at his high school, is in a situation that he has to stop play basketball. Michigan's law is that you can't play sports if you are 19 or older. Eric is a junior, but because of his disability, he held back two years, so he is turning 19 this month. Because basketball team is the only social life, and participated for his life, his dad had requested to the state association's 19-member representative council. After they rejected twice, they finally allowed Eric to play basketball for his senior year.

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  • By: Jiahn O.
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  • Title: Jiahn Oh, 3r hr Biology Enhanced
  • Down Syndrome
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  • Started: almost 4 years ago
  • Updated: over 3 years ago

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